Alan A Melcher: search on Z-Library

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1

Outcome of 132 Operations in 97 Patients With Chordomas of the Craniocervical Junction and Upper Cervical Spine

Choi, David, Melcher, Robert, Harms, Jürgen, Crockard, Alan

Journal:

Year:

2010

Language:

english

File:

PDF, 1.51 MB

english, 2010

2

Using Language Intensity to Increase the Success of a Family Intervention to Protect Children from Ultraviolet Radiation: Predictions from Language Expectancy Theory

David B. Buller, Michael Burgoon, John R. Hall, Norman Levine, Ann M. Taylor, Barbara H. Beach, Charlene Melcher, Mary Klein Buller, Sid L. Bowen, Frank G. Hunsaker, Alan Bergen

Journal:

Preventive Medicine

Year:

2000

Language:

english

File:

PDF, 80 KB

english, 2000

3

6:18179. Multinational prospective observational study of spinal metastasis treated by spinal instrumentation

Ahmed Ibrahim, H. Alan Crockard, Stefano Boriani, Cody Bunger, JüRgen Harms, Christian Mazel, Robert Melcher, Katsuro Tomita

Journal:

The Spine Journal

Year:

2005

Language:

english

File:

PDF, 81 KB

english, 2005

4

Anti–PD-1/anti–CTLA-4 efficacy in melanoma brain metastases depends on extracranial disease and augmentation of CD8 + T cell trafficking

Taggart, David, Andreou, Tereza, Scott, Karen J., Williams, Jennifer, Rippaus, Nora, Brownlie, Rebecca J., Ilett, Elizabeth J., Salmond, Robert J., Melcher, Alan, Lorger, Mihaela

Journal:

Proceedings of the National Academy of Sciences

Year:

2018

Language:

english

File:

PDF, 2.40 MB

english, 2018

5

Evidence for Oncolytic Virotherapy: Where Have We Got to and Where Are We Going?

Turnbull, Samantha, West, Emma, Scott, Karen, Appleton, Elizabeth, Melcher, Alan, Ralph, Christy

Journal:

Year:

2015

Language:

english

File:

PDF, 263 KB

english, 2015

6

The Case of Oncolytic Viruses Versus the Immune System: Waiting on the Judgment of Solomon

Prestwich, Robin J., Errington, Fiona, Diaz, Rosa M., Pandha, Hardev S., Harrington, Kevin J., Melcher, Alan A., Vile, Richard G.

Journal:

Human Gene Therapy

Year:

2009

Language:

english

File:

PDF, 28.04 MB

english, 2009

7

Viral targeting of non-muscle invasive bladder cancer and priming of anti-tumour immunity following intravesical Coxsackievirus A21

Annels, Nicola E, Mansfield, David, Arif, Mehreen, Ballesteros-Merino, Carmen, Simpson, Guy R, Denyer, Mick, Sandhu, Sarbjinder S, Melcher, Alan, Harrington, Kevin J, Davies, BronwYn, Au, Gough, Grose

Journal:

Clinical Cancer Research

Year:

2019

Language:

english

File:

PDF, 2.37 MB

english, 2019

8

Cancer immunotherapy via combining oncolytic virotherapy with chemotherapy: recent advances

Pandha, Hardev, Simpson, Guy, Relph, Kate, Melcher, Alan, Harrington, Kevin

Journal:

Oncolytic Virotherapy

Year:

2016

Language:

english

File:

PDF, 806 KB

english, 2016

9

Autologous versus allogeneic peptide-pulsed dendritic cells for anti-tumour vaccination: expression of allogeneic MHC supports activation of antigen specific T cells, but impairs early naïve cytotoxic priming and anti-tumour therapy

Alison Merrick, Rosa Maria Diaz, Dearbhaile O’Donnell, Peter Selby, Richard Vile, Alan Melcher

Journal:

Cancer Immunology, Immunotherapy

Year:

2008

Language:

english

File:

PDF, 493 KB

english, 2008

10

Differential effects of Paclitaxel on dendritic cell function

Justin John, Mohammed Ismail, Catherine Riley, Jonathan Askham, Richard Morgan, Alan Melcher, Hardev Pandha

Journal:

Year:

2010

Language:

english

File:

PDF, 1.02 MB

english, 2010

11

An Intravenous Stimulus Package for Oncolytic Virotherapy

Vile, Richard, Melcher, Alan

Journal:

Molecular Therapy

Year:

2011

Language:

english

File:

PDF, 223 KB

english, 2011

12

Talimogene laherparepvec in the treatment of melanoma

Appleton, Elizabeth S, Turnbull, Samantha, Ralph, Christy, West, Emma, Scott, Karen, Harrington, Kevin, Pandha, Hardev, Melcher, Alan

Journal:

Expert Opinion on Biological Therapy

Year:

2015

Language:

english

File:

PDF, 750 KB

english, 2015

13

Electromechanical Transduction with Charged Polyelectrolyte Membranes

Grodzinsky, Alan J., Melcher, James R.

Journal:

IEEE Transactions on Biomedical Engineering

Year:

1976

Language:

english

File:

PDF, 4.76 MB

english, 1976

14

Cell death associated with genetic prodrug activation therapy of colorectal cancer

Stephen Todryk, Alan Melcher, Graham Bottley, Michael Gough, Richard Vile

Journal:

Year:

2001

Language:

english

File:

PDF, 213 KB

english, 2001

15

Cytokine-enhanced intravenous oncolytic virotherapy

Donnelly, Oliver, Ilett, Elizabeth, Kottke, Timothy, Thompson, Jill, Vile, Richard, Melcher, Alan

Journal:

Year:

2014

Language:

english

File:

PDF, 52 KB

english, 2014

16

Thunder and Lightning: Immunotherapy and Oncolytic Viruses Collide

Melcher, Alan, Parato, Kelley, Rooney, Cliona M, Bell, John C

Journal:

Molecular Therapy

Year:

2011

Language:

english

File:

PDF, 256 KB

english, 2011

17

STING and IRF3 in stromal fibroblasts enable sensing of genomic stress in cancer cells to undermine oncolytic viral therapy

Arwert, Esther N., Milford, Emma L., Rullan, Antonio, Derzsi, Stefanie, Hooper, Steven, Kato, Takuya, Mansfield, David, Melcher, Alan, Harrington, Kevin J., Sahai, Erik

Journal:

Nature Cell Biology

Year:

2020

File:

PDF, 18.89 MB

2020

18

Human Tumour Immune Evasion via TGF-β Blocks NK Cell Activation but Not Survival Allowing Therapeutic Restoration of Anti-Tumour Activity

Wilson, Erica B., El-Jawhari, Jehan J., Neilson, Abbie L., Hall, Geoffrey D., Melcher, Alan A., Meade, Josephine L., Cook, Graham P., Zimmer, Jacques

Journal:

Year:

2011

Language:

english

File:

PDF, 1.10 MB

english, 2011

19

Cancer Gene Therapy: Part 1. Vector Development and Regulation of Gene Expression

Kevin J. Harrington, Andrew R. Bateman, Alan A. Melcher, Atique Ahmed, Richard G. Vile

Journal:

Clinical Oncology

Year:

2002

Language:

english

File:

PDF, 220 KB

english, 2002

20

Reovirus-associated reduction of microRNA-let-7d is related to the increased apoptotic death of cancer cells in clinical samples

Nuovo, Gerard J, Garofalo, Michela, Valeri, Nicola, Roulstone, Vicki, Volinia, Stefano, Cohn, David E, Phelps, Mitch, Harrington, Kevin J, Vile, Richard, Melcher, Alan, Galanis, Evanthia, Sehl, Sarah,

Journal:

Modern Pathology

Year:

2012

Language:

english

File:

PDF, 772 KB

english, 2012

21

5th International Meeting on Replicating Oncolytic Virus Therapeutics Banff, Alberta, Canada, 18–22 March 2009

Pandha, Hardev, Melcher, Alan, Harrington, Kevin, Vile, Richard

Journal:

Molecular Therapy

Year:

2009

Language:

english

File:

PDF, 208 KB

english, 2009

22

69. Combination Therapy of Reovirus and PD-1 Blockade Effectively Establishes Tumor Control Via Innate and Adaptive Immune Responses

Rajani, Karishma, Shim, Kevin, Parrish, Christopher, Ilett, Liz, Kottke, Tim, Pulido, Jose, Thompson, Jill, Pandha, Hardev, Harrington, Kevin, Melcher, Alan, Errington, Fiona, Diaz, Rosa, Coffey, Matt

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 278 KB

english, 2015

23

Short-course radiotherapy, with elective delay prior to surgery, in patients with unresectable rectal cancer who have poor performance status or significant co-morbidity

Paul Hatfield, Mohan Hingorani, Ganesh Radhakrishna, Rachel Cooper, Alan Melcher, Adrian Crellin, Michelle Kwok-Williams, David Sebag-Montefiore

Journal:

Radiotherapy and Oncology

Year:

2009

Language:

english

File:

PDF, 199 KB

english, 2009

24

Therapeutic Effect of Sodium Iodide Symporter Gene Therapy Combined With External Beam Radiotherapy and Targeted Drugs That Inhibit DNA Repair

Hingorani, Mohan, White, Christine L, Zaidi, Shane, Pandha, Hardev S, Melcher, Alan A, Bhide, Shreerang A, Nutting, Christopher M, Syrigos, Konstantinos N, Vile, Richard G, Vassaux, Georges, Harringto

Journal:

Molecular Therapy

Year:

2010

Language:

english

File:

PDF, 389 KB

english, 2010

25

Optimization of Dendritic Cell Loading With Tumor Cell Lysates for Cancer Immunotherapy

Hatfield, Paul, Merrick, Alison E., West, Emma, OʼDonnell, Dearbhaile, Selby, Peter, Vile, Richard, Melcher, Alan A.

Journal:

Journal of Immunotherapy

Year:

2008

Language:

english

File:

PDF, 474 KB

english, 2008

26

Phase I/II storm study: Intravenous delivery of a novel oncolytic immunotherapy agent, Coxsackievirus A21, in advanced cancer patients

Pandha, Hardev, Harrington, Kevin, Ralph, Christy, Melcher, Alan, Grose, Mark, Shafren, Darren

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2015

Language:

english

File:

PDF, 214 KB

english, 2015

27

Viral targeting of non-muscle invasive bladder cancer and priming of anti-tumour immunity following intravesical Coxsackievirus A21

Annels, Nicola E, Mansfield, David, Arif, Mehreen, Ballesteros-Merino, Carmen, Simpson, Guy R, Denyer, Mick, Sandhu, Sarbjinder S, Melcher, Alan, Harrington, Kevin J, Davies, BronwYn, Au, Gough, Grose

Journal:

Clinical Cancer Research

Year:

2019

File:

PDF, 2.37 MB

2019

28

Inflammatory microenvironment remodelling by tumour cells after radiotherapy

McLaughlin, Martin, Patin, Emmanuel C., Pedersen, Malin, Wilkins, Anna, Dillon, Magnus T., Melcher, Alan A., Harrington, Kevin J.

Journal:

Nature Reviews Cancer

Year:

2020

File:

PDF, 2.55 MB

2020

29

Lack of specificity of cell-surface protease targeting of a cytotoxic hyperfusogenic gibbon ape leukaemia virus envelope glycoprotein

Lucy A. Kirkham, Andrew R. Bateman, Alan A. Melcher, Richard G. Vile, Dr. Adele K. Fielding

Journal:

The Journal of Gene Medicine

Year:

2002

Language:

english

File:

PDF, 205 KB

english, 2002

30

Cancer Gene Therapy: Part 2. Candidate Transgenes and their Clinical Development

Kevin J. Harrington, Alan A. Melcher, Andrew R. Bateman, Atique Ahmed, Richard G. Vile

Journal:

Clinical Oncology

Year:

2002

Language:

english

File:

PDF, 308 KB

english, 2002

31

Fluoride concentration in dentine as a biomarker of fluoride intake in European roe deer (Capreolus capreolus) – An electron-microprobe study

Heiko Richter, Uwe Kierdorf, Alan Richards, Frank Melcher, Horst Kierdorf

Journal:

Archives of Oral Biology

Year:

2011

Language:

english

File:

PDF, 511 KB

english, 2011

32

Circulating markers of biliary malignancy: opportunities in proteomics?

Glenn K Bonney, Rachel A Craven, Raj Prasad, Alan F Melcher, Peter J Selby, Rosamonde E Banks

Journal:

The Lancet Oncology

Year:

2008

Language:

english

File:

PDF, 547 KB

english, 2008

33

Heat Shock Protein Expression in Target Cells Infected with Low Levels of Replication-Competent Virus Contributes to the Immunogenicity of Adenoviral Vectors

Melcher, Alan, Murphy, Stephen, Vile, Richard

Journal:

Human Gene Therapy

Year:

1999

Language:

english

File:

PDF, 613 KB

english, 1999

34

Dendritic Cells for the Immunotherapy of Cancer

Alan Melcher, Andrew Bateman, Kevin Harrington, Atique Ahmed, Michael Gough, Richard Vile

Journal:

Clinical Oncology

Year:

2002

Language:

english

File:

PDF, 109 KB

english, 2002

35

A Family of Bicistronic Vectors to Enhance Both Local and Systemic Antitumor Effects of HSVtk or Cytokine Expression in a Murine Melanoma Model

Castleden, Simon A., Chong, Heung, Garcia-Ribas, Ignacio, Melcher, Alan A., Hutchinson, Gill, Roberts, Bruce, Hart, Ian R., Vile, Richard G.

Journal:

Human Gene Therapy

Year:

1997

Language:

english

File:

PDF, 1.22 MB

english, 1997

36

Oncolytic Viruses: Do They Have a Role in Anti-Cancer Therapy?

Prestwich, Robin J, Errington, Fiona, Harrington, Kevin J., Pandha, Hardev S., Selby, Peter, Melcher, Alan

Journal:

Clinical medicine. Oncology

Year:

2008

Language:

english

File:

PDF, 235 KB

english, 2008

37

What new immunotherapeutic techniques are currently being investigated for the treatment of melanoma?

Donnelly, Oliver G, Melcher, Alan A, Vile, Richard G, Pulido, Jose

Journal:

Year:

2012

Language:

english

File:

PDF, 684 KB

english, 2012

38

Molecular Analysis of Decreased Interleukin-12 Production in Persons Infected with Human Immunodeficiency Virus

Claire Chougnet, Thomas A. Wynn, Mario Clerici, Alan L. Landay, Harold A. Kessler, Janice Rusnak, Gregory P. Melcher, Alan Sher and Gene M. Shearer

Journal:

The Journal of Infectious Diseases

Year:

1996

Language:

english

File:

PDF, 1.57 MB

english, 1996

39

Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression

Melcher, Alan, Todryk, Stephen, Hardwick, Nicola, Ford, Martin, Jacobson, Michael, Vile, Richard G.

Journal:

Nature Medicine

Year:

1998

File:

PDF, 1.02 MB

1998

40

Synergistic effects of oncolytic reovirus and docetaxel chemotherapy in prostate cancer

Lucy Heinemann, Guy R Simpson, Angela Boxall, Timothy Kottke, Kate L Relph, Richard Vile, Alan Melcher, Robin Prestwich, Kevin J Harrington, Richard Morgan, Hardev S Pandha

Journal:

Year:

2011

Language:

english

File:

PDF, 330 KB

english, 2011

41

Impact of antibiotic use during curative treatment of locally advanced head and neck cancers with chemotherapy and radiotherapy

Nenclares, Pablo, Bhide, Sheerang A., Sandoval-Insausti, Helena, Pialat, Pierre, Gunn, Lucinda, Melcher, Alan, Newbold, Kate, Nutting, Christopher M., Harrington, Kevin J.

Journal:

European Journal of Cancer

Year:

2020

File:

PDF, 841 KB

2020

42

Cell Carriers for Oncolytic Viruses: Fed Ex for Cancer Therapy

Willmon, Candice, Harrington, Kevin, Kottke, Timothy, Prestwich, Robin, Melcher, Alan, Vile, Richard

Journal:

Molecular Therapy

Year:

2009

Language:

english

File:

PDF, 354 KB

english, 2009

43

Vesicular Stomatitis Virus-induced Immune Suppressor Cells Generate Antagonism Between Intratumoral Oncolytic Virus and Cyclophosphamide

Willmon, Candice, Diaz, Rosa M, Wongthida, Phonphimon, Galivo, Feorillo, Kottke, Timothy, Thompson, Jill, Albelda, Steven, Harrington, Kevin, Melcher, Alan, Vile, Richard

Journal:

Molecular Therapy

Year:

2011

Language:

english

File:

PDF, 287 KB

english, 2011

44

Synergistic antitumour effects of rapamycin and oncolytic reovirus

Comins, Charles, Simpson, Guy Richard, Rogers, William, Relph, Kate, Harrington, Kevin, Melcher, Alan, Roulstone, Victoria, Kyula, Joan, Pandha, Hardev

Journal:

Cancer Gene Therapy

Year:

2018

Language:

english

File:

PDF, 1.61 MB

english, 2018

45

OP03ONCOLYTIC HERPES SIMPLEX VIRUS INHIBITS PAEDIATRIC HIGH GRADE GLIOMA AND DIFFUSE INTRINSIC PONTINE GLIOMA MIGRATION AND INVASION; MECHANISM AND POTENTIAL FOR CLINICAL APPLICATION

Cockle, Julia V., Ilett, Elizabeth, Brüning-Richardson, Anke, Scott, Karen, Picton, Susan, Short, Susan, Melcher, Alan

Journal:

Year:

2015

Language:

english

File:

PDF, 25 KB

english, 2015

46

The Immunogenic Potential of Recurrent Cancer Drug Resistance Mutations: An In Silico Study

Punta, Marco, Jennings, Victoria A., Melcher, Alan A., Lise, Stefano

Journal:

Frontiers in Immunology

Year:

2020

File:

PDF, 5.15 MB

2020

47

Immunotherapeutic potential of oncolytic virotherapy

Robin J Prestwich, Kevin J Harrington, Richard G Vile, Alan A Melcher

Journal:

The Lancet Oncology

Year:

2008

Language:

english

File:

PDF, 2.16 MB

english, 2008

48

Cytokine Conditioning Enhances Systemic Delivery and Therapy of an Oncolytic Virus

Ilett, Elizabeth, Kottke, Timothy, Donnelly, Oliver, Thompson, Jill, Willmon, Candice, Diaz, Rosa, Zaidi, Shane, Coffey, Matt, Selby, Peter, Harrington, Kevin, Pandha, Hardev, Melcher, Alan, Vile, Ric

Journal:

Molecular Therapy

Year:

2014

Language:

english

File:

PDF, 2.59 MB

english, 2014

49

197. Balancing Anti-Tumor Efficacy with Local Inflammatory Toxicity for the Treatment of Diffuse Intrinsic Pontine Glioma and Other Brain Tumors

Schuelke, Matthew, Evgin, Laura, Kottke, Tim, Thompson, Jill, Driscoll, Christopher, Ilett, Elizabeth, Cockle, Julia, NageswaraRao, Amulya, Bram, Richard, Melcher, Alan, Vile, Richard

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 299 KB

english, 2016

50

Pro-inflammatory cytokine/chemokine production by reovirus treated melanoma cells is PKR/NF-κB mediated and supports innate and adaptive anti-tumour immune priming

Lynette Steele, Fiona Errington, Robin Prestwich, Elizabeth Ilett, Kevin Harrington, Hardev Pandha, Matt Coffey, Peter Selby, Richard Vile, Alan Melcher

Journal:

Molecular Cancer

Year:

2011

Language:

english

File:

PDF, 1017 KB

english, 2011

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